Highly enantioselective iron(II)-catalyzed opening reaction of aromatic meso-epoxides with indoles.
نویسندگان
چکیده
A highly enantioselective method for the catalytic cis-stilbene oxide opening reaction with indole derivatives was developed. The scope of the reaction was studied with a selection of aromatic meso-epoxides and various indoles, and the desired 2-(indol-3-yl)ethanol derivatives were obtained in good to excellent yields with excellent enantioselectivities (from 96 to >99% ee).
منابع مشابه
Iron(II)-catalyzed enantioselective meso-epoxide-opening with anilines.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 43 شماره
صفحات -
تاریخ انتشار 2013